Newborn Screen | Back to Test Directory | ||||
Test Description |
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Screening for certain genetic, endocrine, and metabolic disorders that can affect a child’s long-term health or survival. Early detection, diagnosis, and intervention can prevent death or disability and enable children to reach their full potential. | |||||
Panel Components | |||||
49 inherited conditions including Biotinidase Deficiency, Congenital Adrenal Hyperplasia, Congenital Hypothyroidism, CPT1A Arctic Variant (c.1436C>T) (Alaska only), Cystic Fibrosis, Expanded Screening Disorders, Galactosemia, Hemoglobinopathies, MPS1 Disease (Iowa only), Pompe Disease (Iowa and South Dakota only), Severe Combined Immunodeficiency, and Spinal Muscular Atrophy. | |||||
Reflex Test(s) | |||||
Cystic Fibrosis by Real-Time PCR, Hemoglobinopathies by High Pressure Liquid Chromatography, Pompe Disease Second Tier by Tandem Mass Spectrometry | |||||
Performed | Avg. Turnaround Time | Method | |||
Ankeny 24/7 |
1 - 3 business days | Enzymatic Assay, Immunoassay, IRT Immunoassay, Isoelectric Focusing, Real-Time PCR, Tandem Mass Spectrometry | |||
Fee | CPT Code(s) | ||||
$122.00 | S3620 | ||||
Specimen Requirements | |||||
Specimen Type: | Blood spot specimen | ||||
Collection Instructions: |
Call the Newborn Screening laboratory at 515-725-1630 to obtain a copy of this document or to get assistance in collection of the newborn screen specimen. |
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Temperature and Stability: | Room temperature; submit specimen within 24 hours of collection. | ||||
Unacceptable Conditions: | Blood exhibiting layering, clotting, insufficient quantity, dilution, contamination, serum separation, or didn't soak through the filter paper. | ||||
Expected Results: | Within normal limits, Outside normal limits | ||||
Shipping Instructions | |||||
Place dry specimens into shipping envelope. Send via courier or overnight delivery to: Iowa Newborn Screening Program, State Hygienic Laboratory, 2220 S. Ankeny Blvd., Ankeny, IA 50023-9093. | |||||
Comments | |||||
This is a screening test and not indicated for stand-alone purposes; results should be used in conjunction with other available laboratory and clinical information. A false negative or a false positive result must always be considered when screening; therefore, clinical findings and status should be considered whenever interpreting laboratory results. Newborn reference values may not be applicable to older infants, thus screening results should be interpreted with caution in such cases. Information on the conditions screened is available at https://hhs.iowa.gov/Iowa-Newborn-Screening-Program/For-Families/Conditions-Screened . Collection instructions are based on the Clinical Laboratory Standards institute document NBS01-A6, Blood Collection on Filter Paper for Newborn Screening Programs, Approved Standard – Sixth Edition. |